Mass Spectrometry in Drug Discovery and Development

Mass Spectrometry are extensively used in drug discovery and development, including drug metabolism research. Mass Spectrometry plays in the discovery and development of new therapeutics by both the Pharmaceutical and the Biotechnology Industries. Mass Spectrometry is an essential tool in determining the molecular mass information of interest by ionizing chemical compounds to generate charged molecules or molecule fragments. The most common forms of ionization in small molecule research are electron ionization (EI), atmospheric pressure chemical ionization (APCI), and electrospray ionization (ESI). Mass spectrometry is widely used for analysis of impurities and degradation products due to its high sensitivity and selectivity.

  • Quantitative Analysis by Mass Spectrometry
  • Mass Spectrometry in Small Molecule Drug Development
  • Future Perspectives in Drug Development

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