Mass Spectrometry

Ionization techniques

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In the ion sources, the analyzed samples are ionized prior to analysis in the mass spectrometer. Many ionization techniques are used for mass spectrometry. The most important considerations are the internal energy transferred during the ionization process and the physicochemical properties of the analyte that can be ionized. Some of the ionization techniques are very energetic and cause extensive fragmentation. Other techniques may be softer and may only produce ions of the molecular species.