Mass Spectrometry

Maintenance, Troubleshooting, Data Analysis and Experimentation

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Mass spectrometry(MS) is a high-throughput exploratory technique that describes particles by their mass-to-charge proportion. The MS consist of sample preparation, molecular ionization, detection, and instrumentation analysis processes. MS is beneficial as it is generally fast, requires a small amount of sample, and provides high accuracy measurements. The performance of a mass spectrometer will be severely affected by the lack of a good vacuum in the ion transfer region of the mass analyzer.  With the deterioration of the vacuum, it will become insufficient to maintain biomedical instrumentation in the operating mode. In case if the foreline pump is not maintained, the oil may become so contaminated that the optimum pumping is no longer possible.  Initially, gas transport and metabolism ballasting may refine the oil. On decolorization of the oil it should be changed according to the pump manufacturers maintenance manual.  With the utilization of rotary pumps, to pump away conflict resolution, the solvent may become dissolved in the oil causing an increase in backing line pressure.